Dear Nedoers,

I hope to find you well and safe 🙂

April is coming and the next OnliNedo seminar is approaching: next 9h of April at 12 we have Chiara Poletto, researcher at the  Pierre Louis Institute of Epidemiology and Public Health, as part of the INSERM (France). She is going to present the seminar Diversity in humans and pathogens: effect on epidemics and the impact of interventions on Google Meet at the following address:

Abstract: In the last decades, new network theories and epidemiological evidences have substantially advanced our knowledge about how acute respiratory infections spread in the human population. Temporal and multi-layer networks provide a paradigmatic example. These frameworks allow for clearly describing the heterogeneous connectivity features driving transmission, e.g. different connectivity by settings (household, workplace, school, etc.), and occasional vs. recurrent encounters. However, intrinsic properties of individuals and pathogens, besides individuals’ connectivity are central in shaping the dynamics of transmission. For instance, individuals may be heterogeneous in their susceptibility and their probability to develop a severe form of infection. On the other hand, heterogeneous pathogens and pathogen strains alter the dynamics and burden of an epidemic and are among the drivers of pathogen emergence events. These levels of complexity mutually affect each other which makes it difficult to disentangle their relative role on the epidemic unfolding and the effect of interventions. During the talk I will tackle this issue, presenting recent theoretical and applied works. I will review some studies on the COVID-19 pandemic and discuss the implications of multi-strain/multi-pathogen interaction for the emergence of new pathogens and their co-existence.

Stay safe and be tuNedo,